Our lab is accepting applications for a Postdoctoral Research Associate in the field of drug delivery.
Dr. Kastellorizios’ lab focuses on the following research areas:
1. Translational Research: We are developing novel anticancer nanoparticle characterization methods designed to bridge preclinical and clinical testing. We utilize solid tumor biopsies from cancer patients and test them against existing as well as novel nanomedicine formulations. Our long term goal is to accelerate the discovery of novel anticancer therapies and reduce the associated drug development costs. (Funded by the PhRMA Foundation)
2. Personalized medicine and Health Disparities: we are developing a diagnostic for personalized treatment of metastatic breast cancer, and we are studying its application on breast cancer health disparities in African American women as they apply to nanotherapy outcomes. Our goal is to be able to make sure that each patient or patient group receives the therapy that has the highest chance of success in their particular case. (Funded by NIH NIMHD U54 Texas Center for Health Discparities)
3. Regulatory Science: development of novel quality assurance testing methods for nanoparticle drug products. We apply the principles of Physical Pharmacy and Physical Chemistry to characterize nanoparticle formulations based on their unique interfacial properties. This method will assist in nanomedicine manufacturing in order to reduce drug costs. (Funded by internal UNTHSC funds)
4. Formulation Development and Medical Devices: in collaboration with other researchers that work on new drug candidates, generic drug formulations, and medical devices. These smaller projects are utilized to train Dr. Kastellorizios’ lab members in the science and application of Pharmaceutical Technology. (Funded by Gund-Harrington Foundation in collaboration with UT Austin)
Responsibilities of the position include but are not limited to:
1) Formulation of nano- and micro-particle complex dosage forms
2) Development of bio-mimicking in vitro testing methods for nanoparticle-based formulations to be performed on the International Space Station
3) Characterization of complex dosage form performance in vitro, using biopsies, and in animal models
4) Assistance in lab management and scientific writing (peer reviewed manuscripts, grant proposals, etc.)
Minimum qualifications:
1) PhD in Pharmaceutics, Biomedical or Chemical Engineering, or other closely related field
2) Experience in drug formulation or materials science
3) Strong written and oral communication skills
Preferred qualifications:
1) Experience in cell culture and animal work
2) Experience in 3D printing and prototyping
Apply here.